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Partica LA-960V2

LA-960V2

Laser Scattering Particle Size Distribution Analyzer

HORIBA proudly introduces the newest breakthrough in particle size technology.

This latest evolution in the LA series advances scientific knowledge for tomorrow's world through intuitive software, unique accessories, and high performance.

The LA-960V2 continues HORIBA's proud tradition of leading the industry with innovative design.

Segment: Scientific
Manufacturing Company: HORIBA, Ltd.

HORIBA’s groundbreaking optical design perfects the static light scattering particle sizing technique.

Advanced Detector Design

The number of detectors, angular range, and layout each contribute to overall system performance.

Superior Instrument-to-Instrument Precision

The LA-960V2 is designed and built to provide the same experience regardless of manufacture date, operator skill, or geographic location. Achieve unmatched instrument agreement without the hassle of correlation.

Automatic Laser Alignment in Seconds

Always make perfect measurements with computer-controlled laser alignment. The alignment process is finished in only a few seconds with HORIBA's innovative approach.

Guaranteed Accuracy and Precision

The LA-960V2 is a highly refined particle size analyzer capable of accurately measuring NIST-traceable size standards within 0.6% of specification. Fully compliant with ISO 13320 recommendations regarding the measurement of materials on the D10, D50, and D90.

State of the Art Sampling Systems

Wet Measurement

Sample-to-sample analysis in less than 60 seconds

The HORIBA LA-960V2 wet circulation system is an easy, fast and very powerful dispersion system. The standard wet system offers a full package of a dispersant fill pump, liquid level sensor, circulation pump, 30 W in-line ultrasonic probe, and drain valve, which is all software-controlled for true one-button operation. This advanced design provides highly reproducible particle size results.

Dry Measurement

Automated, powerful dry-powder dispersion

The LA-960V2 PowderJet combines several unique and patented features to provide the most reproducible dry measurements. Use the Auto Measurement function to control vacuum, air pressure, powder flow, start/stop conditions, measurement duration, and data processing. Designed to handle every application including small sample amounts, friable powders, and highly agglomerated materials.

  • Smart Scans – Trigger function
    This function allows for very precious materials to be measured accurately. When the sample amount is limited or low flow ability, the Trigger functions perfectly to start and stop the measurement.
  • Self-Adjusting Powder Flow
    Historically, the biggest challenge in dry powder measurement involved establishing an even powder flow. The LA-960V2 PowderJet has solved that challenge with a self-adjusting feedback loop to maintain a constant laser transmittance. This is a crucial factor in creating reliable, reproducible dry powder size measurements.

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      LY-9610 Imaging Unit

      The imaging unit allows real-time observation, particle image acquisition, and assessment of the particles in the wet circulation system. It is small and integrated in the main unit without increasing instrument footprint!

      Features

      • Detect and count even with trace amounts of unusual particles (Contaminants, large particles and aggregated particles)
      • Detect bubbles in wet circulation system.
      • Improved understanding of sample dispersion (effect of stirring, sonication, addition of surfactants, stabilizers, etc.)
      • Particle shape analysis* (Optional Advanced Software)

       

      Functions

      • Image acquisition and particle detection.
      • Automatic detection of large particles.
      • Automatic detection of bubbles.
      • Real time trend graph and histogram of equivalent circular diameter.
      • Histogram of shape distribution (aspect ratio, roundness, length, width) with optional advanced software.


      See other accessories

      Interview with Dr. Rob Lee of Particle Sciences

      Watch a two minute video detailing how HORIBA Scientific has partnered with Particle Sciences to provide world-class technology and support for their CDMO business.

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            Laser scattering particle size distribution analyzer Model: LA-960V2

            Measurement Principle

            Mie scattering and Fraunhofer diffraction

            Measurement Range

            10 nm - 5000 μm (Option dependent)

            Measurement Time

            Typical measurement takes 60 seconds from liquid filling, sampling and measurement to rinsing.

            Measurement Method

            Circulation measurement or fraction cell measurement (Fraction cell is optional)

            Sample Quantity

            Approximately 10 mg - 5 g (Depending on the particle size, distribution and density)

            Dispersing Volume

            		Approximately 180 mL for standard pumping system, 5/10/15 mL for Fraction Cell accessory, Manual filling : 35 mL, Automatic filling : 40 mL for MiniFlow accessory. Approximately 1 L of LiterFlow option.

            Compatible Liquids

            A type: Water*, S type: Common organic solvents (*also, mixtures with small volumes of ethanol)

            Communication

            USB 2.0 (USB 3.0 required for some options)

            Light Sources

            Red solid state 5 mW laser diode (650 nm), Blue solid state 3 mW LED (405 nm)

            Dispersion System

            In-line ultrasonic probe: 30 W, 20 kHz, adjustable levels
            Circulation pump: Fully automated fill and circulation pumps, 15 adjustable speeds, 4 selectable fill levels, 15 selectable circulation speeds (max: 10 L/min)

            Operating Conditions

            15〜35°C (59 to 95°F), relative humidity 85% or less (no condensation)

            Power

            AC 100-240V 50/60Hz, 300VA

            Dimensions

            705 (W) × 565 (D) × 500 (H) mm

            Mass

            54 kg

            Computer Requirements

            Windows PC with available USB ports, Windows 10 64-bit or Windows 11 64-bit. Contact for additional details.

            scrollable

            ※Windows is a registered trademark of Microsoft Corporation in the United States and other countries.

             

            PowderJet Dry Feeder Accessory

            Dispersion Method

            Compressed air dispersion using Venturi nozzle

            Sample Delivery

            Vibrating feeder

            Sample Disposal

            Vacuum-driven evacuation

            Measurement range

            100 nm - 5000 μm

            Controls

            Communication: Serial cable to LA-960V2 main unit
            Measurement: Vibrating feeder controlled automatically via feedback or manually by user, Vacuum AUTO/OFF, Compressed Air AUTO/OFF, Air pressure adjustable from 0 - 0.4 MPa in 40 steps

            Measurement Time

            Typical measurement takes 2 seconds or longer.

            Operating Conditions for PowderJet

            15〜35°C (59 to 95°F), relative humidity 85% or less (no condensation)

            Dimensions

            332 (W) × 321 (D) × 244 (H) mm (not including dimensions of projections and LA-960V2 measurement unit)

            Power for PowderJet Operation

            AC 100V, 120V, 230V, 50 or 60Hz, 1500VA (Including vacuum but LA-960V2 measurement unit)

            Compressed Air Supply Pressure

            Compressed air supply origin pressure: 0.4 - 0.8 MPa
            Compressed air controlling range: 0.01 - 0.4 MPa

            Compressed Air Connection

            Quick connector for resin tube with 6 mm outer diameter
            (Compressed air supply equipment must be provided separately)

            Remarks

            Vacuum is equipped as standard

            scrollable

            ※When ordering the PowderJet, please specify the power requirements for the final destination.
            ※Above specifications and functionality are valid only when PowderJet is installed on the LA-960V2 main unit and controlled using the LA-960V2 software.
            ※Manufacturers and models indicated for vacuum, air compressor, computer, monitor, and/or printer are subject to change.

            ◎Air Compressor
            Inlet pressure within 0.5 - 038 MPa, Tank capacity 26 L or larger, Flow rate 45 L/min or faster

             

            LY-9610 Imaging Unit

            Observed Measurable Range
            for image analysis            		5 μm - 1000 μm*
            *5 μm for size and 9 μm for shape as per ISO 13322-2.
            Pixel Size0.8 μm
            Speed≧ 4 fps
            FunctionsHistogram of equivalent circle diameter.
            Shape Parameters: Aspect ratio*, Circularity*, Length*, Width*
            Trend graph of equivalent circle diameter.
            Post Analysis of captured image (zoom-in/out, measuring size).
            CommunicationUSB 3.0
            scrollable

              *Optional Advanced software

            Accessories

            Components
                         		LA-960N2LA-960A2LA-960S2LA-960W2LA-960L2
            OpticsStandard optical system•••••
            Aqua type Ethanol can be used as a dispersing additive. (0.01 - 3000 μm）   


                         		Standard circulation system-•---
            Pressurized fill adapter---•-
            Liter flow----•
            Peristaltic pump system---•-
            Solvent type（0.01 - 3000 μm）Standard pump system--•--
            AccessoriesFraction cell holder•••••
            Mini-Flow with ultrasonic unit (0.01 - 1000 μm)•••••
            Paste cell holder•••••
            Dry unit (0.1 - 5000 μm）•••••
            Auto sampler-••••
            High Concentration Cell•••••

            Imaging Analysis Unit

            		-••••
            scrollable

            External Dimensions (mm)

            Filter
            Laser Diffraction Analysis of Lithium Ion Battery Material
            Laser Diffraction Analysis of Lithium Ion Battery Material
            Battery technology is improving, keeping up with the demand for better power storage. Improved performance requires greater control of the materials used and their physical properties including the particle size distribution.
            Read more
            Particle Sizing of Alkaline Battery Materials
            Particle Sizing of Alkaline Battery Materials
            Alkaline batteries have unique features compared to zinc-carbon batteries, including high energy density, a wide operating temperature range, high current capability, and a leak-proof design. They are also used for a wide range of purposes. The alkaline battery is generally made with a positive electrode consisting of a mixture of manganese oxide and graphite, a negative electrode of zinc, and an electrolyte solution of potassium hydroxide.
            Read more
            Particle Size Distribution of Black Toner
            Particle Size Distribution of Black Toner
            Toner is a primary component of the electrophotographic printing and copying processes. The synthesized toner particles must exhibit some special characteristics such as particle size and shape to obtain high quality and high-resolution printed images. Utilization of smaller particle size toners has been suggested to be effective in achieving high image quality. In this study, the analysis of the particle size distribution of black toner is optimized using HORIBA Partica LA-960V2 laser diffraction particle size distribution analyzer.
            Read more
            Calcium Carbonate Particle Sizing for Paint and Coating Applications
            Calcium Carbonate Particle Sizing for Paint and Coating Applications
            A pigment obtains, for example, its maximum colour effect only in a narrow particle size range below 1 to 2 microns. Therefore, understanding particle size distribution of calcium carbonates becomes one of the foremost parameters to be examined. In this study, the particle size distribution of the two different grades of calcium carbonate was investigated using HORIBA Partica LA-960V2 Laser Scattering Particle Size Distribution Analyzer.
            Read more
            Particle Analysis of CMP Slurries
            Particle Analysis of CMP Slurries
            The abrasive particles found in CMP slurries have a size distribution which directly affects critical metrics. Particle size analysis is therefore a key indicator of CMP slurry performance. The popularity and utility of several particle sizing techniques will be discussed within.
            Read more
            Particle Analysis for Cosmetics
            Particle Analysis for Cosmetics
            Many cosmetic products include particulate material or emulsions. Some examples of cosmetic products consisting of or including particulates include facial powders, moisturizers, and lipstick. The particle size distribution of these components effects appearance, stability, and protection.
            Read more
            Maximizing Soy Milk Quality Attributes through Particle Size Analysis
            Maximizing Soy Milk Quality Attributes through Particle Size Analysis
            In this note, the final result of soy milk processing is evaluated with particle size analysis. Particle size results give a quantitative measure of the soy milk that can be used to ensure consistent production and product quality.
            Read more
            Particle Analysis of Mayonnaise
            Particle Analysis of Mayonnaise
            This application note reviews the important role that particle size plays in the formation of mayonnaise and mayo products and how changes affect the taste and consistency of these alternatives.
            Read more
            Material Characterization of the Next Generation Sugar Substitutes
            Material Characterization of the Next Generation Sugar Substitutes
            This study focuses on the critical particle diameter of dry sugar granules as particle diameter is an indicator of: Flowability, Dissolution and mixing, and Powder uniformity.
            Read more
            Particle Size Analysis of Piezoelectric Ceramics
            Particle Size Analysis of Piezoelectric Ceramics
            This application note shows how the laser diffraction technique can be effectively used as an inspection tool for the synthesis of piezoelectric ceramics.
            Read more
            Pigment Particle Size and Hiding Power
            Pigment Particle Size and Hiding Power
            Pigment size can be readily measured by laser diffraction. This measurement requires less time, training and effort than a color strength measurement and provides useful information for the process engineer.
            Read more
            Particle Characterization of Coffee
            Particle Characterization of Coffee
            The HORIBA LA-960 laser diffraction particle size analyzer can cover all sizes of coffee grounds. Using laser diffraction leads to significant time and labor savings in addition to a more objective, reliable, and robust measurement.
            Read more
            Particle Size Matters When it Comes to CBD Stability and Bioavailability
            Particle Size Matters When it Comes to CBD Stability and Bioavailability
            In this Application Note, we will focus on the importance of monitoring particle size and distribution range throughout two different processing technologies used to improve shelf-life and efficacy of CBD products.
            Read more
            Titanium Dioxide Particle Size
            Titanium Dioxide Particle Size
            Titanium Dioxide (TiO2) is a pigment used in paints and many other applications. The particle size of titanium dioxide directly impacts its performance in numerous applications, necessitating the measurement and control of this important property.
            Read more
            Particle Characterization of Nutraceutical Products
            Particle Characterization of Nutraceutical Products
            Laser diffraction particle size analyzers offer the same benefits in speed, precision, and reliability to nutraceutical materials that have made the technique popular in the pharmaceutical industry.
            Read more
            Analysis of Biopolymers with Laser Diffraction
            Analysis of Biopolymers with Laser Diffraction
            This application note describes two experiments where laser diffraction proved capable of determining both the base biopolymer nanoparticles and also larger particles outside of the range of DLS.
            Read more
            Particle Analysis of Gold Nanoparticles
            Particle Analysis of Gold Nanoparticles
            Nanoparticle gold is a suspension of sub-micron gold particles typically dispersed in water. Gold nanoparticles are of great interest for researchers in many fields due to their unique physical and optical properties. These properties change with the particle size distribution, so size analysis is an important measurement requirement.
            Read more
            Particle Size of Electronic Ceramic Powders
            Particle Size of Electronic Ceramic Powders
            Particle size analysis plays a crucial role in the manufacture of electronic materials for dielectric applications. In all cases, the particle size distribution has a great impact on their processing and performance.
            Read more
            Laser Diffraction Particle Size Analysis of Solid Oxide Fuel Cell Materials
            Laser Diffraction Particle Size Analysis of Solid Oxide Fuel Cell Materials
            Particle size is of critical importance to the powder properties and to the performance of solid oxide fuel cells. Laser diffraction has proven to be an excellent way to monitor and control particle size for these materials.
            Read more
            Measuring Organic Pigments with Laser Diffraction
            Measuring Organic Pigments with Laser Diffraction
            Particle size is a critical physical characteristic of pigments and laser diffraction is the most popular method of particle size analysis for the milling process, allowing close control and optimization of a number of final product performance criteria.
            Read more
            Particle Size Analysis of Cement
            Particle Size Analysis of Cement
            Measuring and controlling the particle size distribution of cement is important both in order to achieve the desired product performance and to control manufacturing costs. Laser diffraction is the more popular method to determine the particle size distribution as the technique is quick, easy, reproducible, and provides a complete picture of the full size distribution.
            Read more
            Laser Diffraction Analysis of Soils and Sediments
            Laser Diffraction Analysis of Soils and Sediments
            Measurement of the particle size of soil and sediment sample is a critical part of understanding the geological history of a particular area.
            Read more
            Rapid Particle Size Analysis of Topical Ophthalmic Formulations
            Rapid Particle Size Analysis of Topical Ophthalmic Formulations
            Drug particle size and distribution are key critical quality attributes that govern stability, ocular retention via solution thickness, and therapeutic release characteristics. The laser diffraction technique is an elegant method used to establish the fundamentals of ophthalmic formulations prior to pharmacokinetic or clinical studies. To fulfill the requirements set out by the FDA, our recommendation is the Partica LA-960V2 Particle Size Analyzer.
            Read more
            Guide to D-values in Pharmaceutical Particle Characterization
            Guide to D-values in Pharmaceutical Particle Characterization
            It is necessary to have a particle size quantification system better suited to the specific requirements of the pharmaceutical industry; and D-values, while basic, fit this requirement well.
            Read more
            DLS vs. Diffraction of Flavor Emulsions
            DLS vs. Diffraction of Flavor Emulsions
            The particle size distribution of many flavor emulsions has a substantial effect on their performance. Particle size distribution can affect mouth feel, appearance, and emulsion stability.
            Read more
            Particle Characterization of Powdered Sugar
            Particle Characterization of Powdered Sugar
            Quality control is an essential part of sugar production. In this study, the LA-960V2’s ability to rapidly analyze particle separation and the particle size of powdered sugar at its de-agglomerated state is demonstrated.
            Read more
            Particle Size Determination of Mineral-Based Sunscreens: A Complex Analytical Application
            Particle Size Determination of Mineral-Based Sunscreens: A Complex Analytical Application
            Mineral-based sunscreens have gained popularity due to their excellent ability to scatter ultraviolet (UV) rays without causing photo-induced skin irritation from chemical-based sunscreens. Of the 18 U.S. Food and Drug Administration approved active ingredients for sunscreen drug products, only two are mineral based. Zinc oxide remains stable at high temperature and in neutral pH, covers a broad spectrum of UV radiation, and is even mildly antibacterial. Three over-the-counter zine oxide sunscreens were purchased and analyzed using Partica LA-960V2 Laser Diffraction Particle Size Analyzer. A standard 15 mL fraction cell accessory fitted with a magnetic stir bar was chosen for this experiment.
            Read more
            Study of Particle Size in Food Industry: Wheat Flour
            Study of Particle Size in Food Industry: Wheat Flour
            In this study, particle size of wheat flour is measured by laser diffraction technology that has emerged as the most important and effective technique in the world of particle size analysis. When compared with traditional sieve method, laser diffraction is fast, non-destructive, and provides automated measurement through a simple measurement workflow.
            Read more
            Particle Size and Shape of Abrasives
            Particle Size and Shape of Abrasives
            The behavior of an abrasive material is influenced by the hardness, size, and shape of the particles. A harder particle will be more aggressive in altering the surface of the work piece. Larger particles generate higher impact force removing the material surface quicker and producing a heavier texture. Particle shape also plays a role.
            Read more
            Frac Sand and Proppant Size and Shape
            Frac Sand and Proppant Size and Shape
            Hydraulic fracturing is used in the oil and gas industry to increase the flow of oil and/or gas from a well. Proppants are pumped into the oil well with fracturing fluid to hold the fissures open. The proppant size, shape, and mechanical strength influences the integrity of the newly created fractures, and therefore the flow of oil and gas out of the well.
            Read more
            Metal Powder Size Measurement
            Metal Powder Size Measurement
            Virtually any metal can be made into a powder through processes including atomization, electrolysis, chemical reduction, and size comminution. The metal powder can then be used to fabricate parts from simple to complex shape. The technique and study of these processes is known as powder metallurgy, a field of study well acquainted with particle characterization. The size distribution and shape of the powder metal particles influences the physical properties of the parts created.
            Read more
            Particle Analysis in Vaccine Manufacturing and Development
            Particle Analysis in Vaccine Manufacturing and Development
            Size matters in vaccine delivery systems. Nanoparticles smaller than 200 nm generally present a greater immunogenic response than micro-particles larger than 1 micron.
            Read more
            Particle Size of Paper Chemicals
            Particle Size of Paper Chemicals
            To control the properties of paper, certain materials may be used during manufacturing. The particle size distribution of these materials directly affects properties such as gloss, brightness, opacity, color bleed, ink mileage, and more.
            Read more
            Particle Analysis in Polymers & Plastics
            Particle Analysis in Polymers & Plastics
            Polymers are large molecules made from repeating structural units connected by covalent chemical bonds. We often use the word ‘plastic’ to refer to polymeric materials, but polymers also include a wide range of natural materials such as proteins, DNA, cellulose, shellac and amber.
            Read more
            Particle Analysis for Power Plant Emission Control
            Particle Analysis for Power Plant Emission Control
            The importance of particle size for power plants is found in their ability to meet environmental regulations while controlling capital expenditures and operating costs. This application page will show how investing in particle size analysis helps control operating costs and improve margins for power plants.
            Read more
            Protein Aggregation and Size Analysis
            Protein Aggregation and Size Analysis
            The study of protein aggregation encompasses a broad range of interactions and mechanisms. The LA-960 laser diffraction particle size analyzer possesses the unique ability to measure from 10 nanometers to 5 millimeters, accurately detecting the aggregates and, in some cases, the primary protein size.
            Read more
            Particle Analysis of Road Materials
            Particle Analysis of Road Materials
            Asphalt emulsions are droplets of asphalt dispersed in water with the aid of an emulsifying agent. Particle size of the asphalt droplets is critical to stability and application performance.
            Read more
            Viruses and Virus-Like Particles
            Viruses and Virus-Like Particles
            A virus particle consists of several parts including the genetic material (DNA or RNA), a protein coat that protects these genes, and in some cases an envelope of lipids that surrounds the protein coat when they are outside a cell.
            Read more
            Comparison of results between laser diffraction and image analysis
            Comparison of results between laser diffraction and image analysis
            Laser diffraction is a popular method for particle characterization. Coupled with an image analysis unit, we can compare in real time the classical values of D10, 50, 90 and get information about the shape or dispersion state of our particles, thus proving the usefulness of this complementary technique.
            Read more
            Characterizing Battery Materials by Particle Size and Shape Analysis and Raman Spectroscopy
            Characterizing Battery Materials by Particle Size and Shape Analysis and Raman Spectroscopy
            As the requirements for electric vehicles and other portable devices become more and more demanding, the need for higher performance batteries and the ability to monitor the battery material’s physical and chemical characteristics will continue to increase. Of the novel battery materials finding more usage in rechargeable lithium-ion batteries are lithium iron phosphates (LFPs), used to comprise the cathode, and carbon-coated silicon (Si@C), used to make the anode.
            Read more

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            Particle Guidebook
            Size: 4.18 MB
            Accelerating Pharmaceutical Advancements Brochure

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