在单细胞水平上实现微生物的拉曼光谱研究

Identification of contaminating microbes is an important public safety issue in many fields such as the control of food quality and the manufacture of pharmaceutical and cosmetic products. Previous research has shown the potential for Raman spectroscopy in combination with chemometric methods to investigate bulk samples as well as a single bacterium and yeast cell for classification on the species and strain level.